Bactria was a province of the Persian empire located in modern Afghanistan, Uzbekistan, and Tajikistan. After the defeat of Darius III of Persia, Bactria continued to offer resistance against Alexander the Great, led by Bessus, who had proclaimed himself successor to Darius. Alexander conquered it with great difficulty between 329-327 BCE, largely with the help of local auxiliary forces. During his stay there, Alexander married a Bactrian woman, Roxanne, to aid his effort of controlling the region.

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